Heavy smoking linked to atrophy in Alzheimer’s brain regions

	Alzheimer's Disease
	The latest Alzheimer's disease news from News Medical

	Heavy smoking linked to atrophy in Alzheimer’s brain regions MRI findings indicate that smoking is linked to reduced brain volume, raising concerns about dementia risk, especially with higher body mass index.

	AI identifies novel gene variants linked to Alzheimer’s risk This study reveals how machine learning models uncover new genetic variants linked to Alzheimer’s, advancing predictive accuracy in genetic epidemiology.

			Mathematics offers new clues in the fight against Alzheimer's Mathematics may not be the first thing people associate with Alzheimer's disease research. But for Pedro Maia, an assistant professor of mathematics and data science at The University of Texas at Arlington, analyzing how different parts of the brain interact like a network is revealing new insights into one of the world's most devastating brain disorders.

			Greener cities reduce dementia risks linked to air pollution Boosting greenery may protect against air pollution's impact on dementia, revealing a potential strategy to reduce Alzheimer's disease burden globally.

			Study: Formal education does not slow brain aging or cognitive decline An international study published in the journal Nature Medicine casts doubt on the widespread belief that higher levels of formal education directly protect against cognitive decline and brain aging.

	UCSF discovery points to new strategies for Alzheimer's treatment UCSF scientists have discovered how microglia engulf and break down amyloid beta, a protein that builds up in Alzheimer's, with devastating consequences for the brain.

	New research shows neurogenesis slows in early adulthood, impacting memory Age often brings a gradual decline in the ability to learn new things and retain memories. This phenomenon, often associated with the elderly, is linked to the brain's deteriorating capacity to generate new neurons-a process that primarily occurs in the hippocampus -as neural stem cells (NSCs) divide and mature. Recent research suggests this decline begins much earlier in life than previously thought, potentially starting in early adulthood.

	Addressing diagnostic delays in dementia for better patient outcomes People with dementia are diagnosed an average of 3.5 years after symptoms are first noticed, or even longer (4.1 years) for those with early-onset dementia, finds a new study led by UCL researchers.

	Brain’s blood vessels and immune cells play key role in Alzheimer’s and stroke The brain's health depends on more than just its neurons. A complex network of blood vessels and immune cells acts as the brain's dedicated guardians-controlling what enters, cleaning up waste, and protecting it from threats by forming the blood-brain barrier.

	Antiviral treatment shows no benefit for early Alzheimer’s patients The idea that herpes infections trigger or contribute to Alzheimer's disease has been gaining favor among some scientists, raising hope that herpes treatments could slow progression of Alzheimer's symptoms among patients.

	Is “Mom Brain” Real? The Science Behind Memory, Mood, and Motherhood Pregnancy and motherhood trigger profound hormonal, structural, and functional changes in the brain, reshaping neural circuits to support caregiving and maternal behaviors. Recent evidence reveals that “mom brain” reflects adaptive neuroplasticity rather than simple cognitive decline.

	PD-1 helps guide immune memory cells to the skin early during infection Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune defenders in the skin.

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