BioIVT Neuroscience Symposium Presentations Now Available

	Neurology & Neuroscience
	The latest neurology news from News Medical

Watch recordings and download slides for:

Translating Diversity and Longitudinal Data into Discovery
Leveraging MS-Based Proteomics to Drive Biomarker Discovery
Transporting your way around the CNS
Restoring UNC13A as a treatment for people with ALS

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			Gene editing in the brain offers hope for ultra-rare neurological disease Scientists have corrected gene mutations in mice causing an ultra-rare disease by editing DNA directly in the brain with a single injection, a feat with profound implications for patients with neurological diseases.

			APOE ε4 variant reveals hidden risk factors beyond Alzheimer’s Researchers discovered that people carrying the APOE ε4 gene variant share a unique immune-related protein signature across their blood, brain, and cerebrospinal fluid—regardless of neurodegenerative disease diagnosis. This signature reveals a fundamental, disease-independent vulnerability linked to APOE ε4, reframing our understanding of genetic risk in conditions like Alzheimer's, Parkinson’s, ALS, and FTD.

	Study identifies mechanism that helps prevent cancer, neurodegeneration, and premature aging Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA damage that causes cancer, neurodegeneration, and premature aging.

	New insights into brain fueling could lead to treatments for stroke, neurodegeneration A new Yale study has revealed that neurons - the energy-hungry cells that connect and direct activity in the brain - are equipped with "backup batteries" that kick in to keep the brain running during periods of metabolic stress.

	Interbreeding with Neanderthals may explain risk for fatal neurological condition in modern humans A new Simon Fraser University-led study reveals interbreeding between humans and their ancient cousins, Neanderthals, as the likely origin of a neurological condition estimated to impact up to one per cent of people today.

	Prime editing reverses symptoms of severe childhood neurological disease Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations that cause alternating hemiplegia of childhood, a rare and severe neurological disorder that begins in infancy.

	Weill Cornell Medicine launches study to advance treatments for rare neurological disorder A $1.1 million grant from the parent-caregiver-led Rare Bird Foundation to Weill Cornell Medicine is supporting the launch of a natural history study for a rare neurodevelopmental disorder that causes developmental delays and seizures called MEF2C Haploinsufficiency syndrome (MCHS).

	Researchers honored for groundbreaking work in cancer neuroscience The University of Virginia School of Medicine's Harald Sontheimer, PhD, and Stanford's Michelle Monje, MD, PhD, have received the 2025 International Prize in Translational Neuroscience from the Gertrud Reemtsma Foundation for their pioneering research in the emerging field of cancer neuroscience.

	Neuron-Like Telocytes Directly Connect to Stem Cells in the Intestine In a key advance for regenerative medicine and gut health, scientists from Duke-NUS Medical School and Nanyang Technological University, Singapore (NTU Singapore) have uncovered a precise and unexpected communication system in the gut.

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