Heavy smoking linked to atrophy in Alzheimer’s brain regions

	Radiology
	The latest radiology news from News Medical

	Heavy smoking linked to atrophy in Alzheimer’s brain regions MRI findings indicate that smoking is linked to reduced brain volume, raising concerns about dementia risk, especially with higher body mass index.

	FDA Breakthrough Device designation granted for AI-based mammogram analysis tool A new technology that harnesses AI to analyze mammograms and improve the accuracy of predicting a woman's personalized five-year risk of developing breast cancer has received Breakthrough Device designation from the Food and Drug Administration (FDA).

			AI algorithm identifies one-third of missed breast cancers in DBT screenings An AI algorithm for breast cancer screening has potential to enhance the performance of digital breast tomosynthesis (DBT), reducing interval cancers by up to one-third, according to a study published today in Radiology, a journal of the Radiological Society of North America.

			Machine learning model predicts radiotherapy response in patients with nasopharyngeal carcinoma Researchers in China have developed a powerful machine learning model that can help determine which patients with nasopharyngeal carcinoma (NPC) are likely to respond well to radiotherapy-a common treatment for this type of cancer.

			T cell senescence shapes cancer prognosis and immunotherapy response T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by tumor-associated antigens, metabolic pathway alterations, activation of chronic inflammatory responses, proliferation of immunosuppressive cells, and T cell damage caused by tumor radiotherapy and chemotherapy.

	Researchers map key mechanism for bladder function Urinary incontinence is a devastating condition affecting over 33 million Americans, according to the National Association for Continence, leading to significant adverse impacts on patients' mental health and quality of life. Disorders of urination are also a key feature of all neurological disorders.

	Innovative technologies push pediatric MRI beyond diagnostics From fetal stages through adolescence, the b;rain undergoes rapid, layered development—from basic motor skills to complex emotional regulation.

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