Analytical Chemistry in Life Sciences - Development of a Platform SEC-MALS Method for Therapeutic mABS
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Introducing Octet<sup>®</sup> R8e BLI System With Unprecedented SensitivityIntroducing Octet® R8e BLI System With Unprecedented Sensitivity

Sartorius launches the new Octet® R8e biolayer interferometry (BLI) system, providing researchers with its most advanced detection capabilities to date for real-time, high-throughput analysis of protein-protein, protein-small molecule, and other biomolecular interactions. Expanding the industry-leading fluidic-free Octet® BLI portfolio, the R8e is designed for applications requiring higher sensitivity, flexible assay design, and longer run times.

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    Development of a Platform SEC-MALS Method for Therapeutic mABSDevelopment of a Platform SEC-MALS Method for Therapeutic mABS
 
Size variants of therapeutic mAbs is crucial to ensuring product quality in manufacturing. This application note describes platform SEC-MALS technique for analyzing size distribution of mAbs, thereby increasing efficiency.
 
Read the App Note
 
 
   Fruit Fly Study Uncovers Key Mechanisms Behind Collective Cell MigrationFruit Fly Study Uncovers Key Mechanisms Behind Collective Cell Migration
 
Researchers uncover how Plexin A and Semaphorin 1b regulate collective cell migration in fruit fly testes, offering insights into organ development, cancer metastasis, and tissue engineering.
 
 Digging into the past: What ancient proteins say about real medieval meals
 
Digging into the past: What ancient proteins say about real medieval mealsResearchers used stable isotope and proteomic analyses on medieval European skeletons to uncover the details of ancient diets. The findings revealed a heavy reliance on C3 plants, terrestrial animal proteins, legumes, and freshwater fish, demonstrating the power of combining methods for paleodietary reconstruction.
 
 
 Tridecanoic Acid (C13): The Odd-Chain Fatty Acid With Big Implications
 
Tridecanoic Acid (C13): The Odd-Chain Fatty Acid With Big ImplicationsTridecanoic acid (C13) is a rare, odd-chain saturated fatty acid produced mainly by gut and rumen microbes, entering metabolic pathways via β-oxidation to support gluconeogenesis and the TCA cycle. Although scarcely detected in plasma, emerging research suggests C13 could serve as a sensitive biomarker for diet-microbiome interactions and may have distinct metabolic and anti-inflammatory effects.
 
 
 Muscle-derived vesicles heal damaged cells and reverse disease in new study
 
Muscle-derived vesicles heal damaged cells and reverse disease in new studyResearchers discovered that mitochondria-rich extracellular vesicles (Ti-mitoEVs) from skeletal muscle can deliver healthy mitochondria to damaged cells, restoring energy and promoting tissue repair in mice. The approach reversed acute muscle injury and chronic kidney disease, offering a promising new regenerative therapy.
 
 
 Do Popular Skincare Ingredients Like Niacinamide and Retinol Actually Work?
 
Do Popular Skincare Ingredients Like Niacinamide and Retinol Actually Work?This article critically reviews leading cosmeceutical ingredients, including niacinamide, retinoids, vitamin C, hyaluronic acid, peptides, and sunscreens, focusing on their evidence base, mechanisms, and clinical effects. It highlights efficacy, safety profiles, formulation challenges, and areas where robust research is needed to support dermatological recommendations.
 
 
 Customizable, Fast-degrading Food Wrap to Cut Landfill
 
Customizable, Fast-degrading Food Wrap to Cut LandfillResearch on chitosan-PCL films reveals enhanced durability and biodegradability, offering sustainable solutions for food packaging and pollution reduction.
 
 

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