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New gravity-based method improves platelet-rich plasma extraction

Platelet-rich plasma (PRP) is a fraction of blood plasma; its concentration of platelets is of great value in regenerative medicine as they are essential in accelerating healing and repairing tissue.

24 Jul 2025

Different anti-PD-L1 antibodies show varied results in tumor growth inhibition

Immune checkpoint inhibitors (ICIs), a powerful form of immunotherapy, have revolutionized cancer treatment by unleashing the body's own immune system to fight tumors.

24 Jul 2025

High-resolution whole-cortex imaging reveals neurovascular dynamics in awake mice

Neurovascular coupling (NVC) is the dynamic regulation of cerebral blood flow in response to neural activity. Specifically, when neurons become active, nearby blood vessels dilate to increase blood supply, thereby meeting the heightened energy demands associated with neural activity.

24 Jul 2025

New redox-sensitive pathway reveals how cells activate AMPK in response to metabolic stress

AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress.

24 Jul 2025

Ketamine's antidepressant effects involve the brain's opioid system

Ketamine is a highly effective, fast-acting antidepressant that works even for patients who have not responded to other medications.

24 Jul 2025

Penn State team investigates the neural basis of nightmares and mental health

Dreams, and likely nightmares, are experienced universally across humans and animals, but neuroscientists still do not know why.

24 Jul 2025

Scientists discover neuron-like communication system in the gut

In a key advance for regenerative medicine and gut health, scientists from Duke-NUS Medical School and Nanyang Technological University, Singapore (NTU Singapore) have uncovered a precise and unexpected communication system in the gut.

24 Jul 2025

CoVerage outperforms rivals in early detection of COVID mutations

The CoVerage system monitors SARS-CoV-2 evolution, predicting variants and scoring amino acid changes to inform vaccine efficacy and public health strategies.

24 Jul 2025

AI identifies novel gene variants linked to Alzheimer’s risk

This study reveals how machine learning models uncover new genetic variants linked to Alzheimer’s, advancing predictive accuracy in genetic epidemiology.

24 Jul 2025

Gut bacteria send direct signals to the brain to stop you from overeating

Researchers have discovered a novel gut-brain sensory circuit in mice where specialized colonic cells sense bacterial flagellin and rapidly suppress feeding via the vagus nerve. This "neurobiotic sense" operates independently of immune pathways, revealing a direct neural mechanism for microbiota-host communication.

24 Jul 2025

Digging into the past: What ancient proteins say about real medieval meals

Researchers used stable isotope and proteomic analyses on medieval European skeletons to uncover the details of ancient diets. The findings revealed a heavy reliance on C3 plants, terrestrial animal proteins, legumes, and freshwater fish, demonstrating the power of combining methods for paleodietary reconstruction.

24 Jul 2025

How much does online negativity really affect your mind?

Negative comments on social media can significantly increase anxiety and lower mood in adults, according to a new experimental study. Younger adults are particularly susceptible to the psychological effects of online negativity.

23 Jul 2025

Study reveals pandemic life made brains age faster, even without catching COVID-19

The COVID-19 pandemic accelerated biological brain aging in older adults by an average of 5.5 months over less than three years, regardless of infection status. Social disruption, age, male sex, and socioeconomic disadvantage heightened vulnerability, while only infected individuals showed measurable declines in executive function.

23 Jul 2025