Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Scientists uncover why Lyme disease symptoms may linger after treatment

Symptoms that persist long after Lyme disease is treated are not uncommon - a 2022 study found that 14% of patients who were diagnosed and treated early with antibiotic therapy would still develop Post Treatment Lyme Disease (PTLD).

23 Apr 2025

Scientists uncover surprising new link between gut health and blood cancer risk

Scientists at Cincinnati Children's along with an international team of researchers have discovered a surprising new connection between gut health and blood cancer risk-one that could transform how we think about aging, inflammation, and the early stages of leukemia.

23 Apr 2025

New recommendations for the treatment of familial Mediterranean fever

In 2016, EULAR - The European Alliance of Associations for Rheumatology - published recommendations on the treatment of familial Mediterranean fever (FMF). Since then, new evidence has become available, so the recommendations have been reviewed and updated.

23 Apr 2025

FDA approved anti-inflammatory drug shows promise for treating alcohol use disorder and pain

A preclinical study from scientists at Scripps Research finds that a drug already FDA-approved for treating inflammatory conditions may help reduce both alcohol intake and pain sensitivity-two issues that commonly co-occur with alcohol use disorder (AUD).

22 Apr 2025

Targeting zombie cells could revolutionize chronic back pain treatment

In a preclinical study led by McGill University researchers, two drugs targeting "zombie cells" have been shown to treat the underlying cause of chronic low back pain. The condition affects millions of people worldwide.

22 Apr 2025

New subtype of Castleman disease identified to improve diagnosis and treatment

A newly identified subtype of Castleman disease will help diagnose and properly treat thousands of patients who have been caught between existing classification systems, marking the first major discovery of its kind in 45 years.

22 Apr 2025

Exploring citrullination as a key regulator of gene expression and disease

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

20 Apr 2025

RFK Jr. struggles to navigate frustrated supporters and a demanding boss

After the Senate voted to confirm Robert F. Kennedy Jr. as Health and Human Services secretary, supporters of his "Make America Healthy Again" movement cheered at having a champion in the federal government.

17 Apr 2025

Gut bacteria turn bile acids into allies against cancer

Bacteria naturally present in the human intestine, known as the gut microbiota, can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study led by Weill Cornell Medicine investigators.

16 Apr 2025

New genetic study reveals hundreds of clues to osteoarthritis

About one in five American adults have osteoarthritis, the most common form of arthritis, according to the Centers for Disease Control and Prevention.

15 Apr 2025

Understanding the complex spectrum of Castleman disease

Castleman disease (CD) is a rare, non-clonal lymphoproliferative disorder that manifests with a wide range of histologic and clinical features.

11 Apr 2025

Refining the diagnosis of large granular lymphocytic leukemias and their mimics

Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal proliferation of cytotoxic lymphocytes. Among them, T-cell LGLL (T-LGLL) and NK-cell LGLL (NK-LGLL) are the most prominent.

10 Apr 2025

Study reveals brain circuit behind apathy in advanced cancer

The fatigue and lack of motivation that many cancer patients experience near the end of life have been seen as the unavoidable consequences of their declining physical health and extreme weight loss.

10 Apr 2025

Calibr-Skaggs receives FDA approval to test sCAR-T therapy in patients with autoimmune diseases

Calibr-Skaggs Institute for Innovative Medicines, the drug discovery division of Scripps Research, announced today that the FDA has cleared their investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy (CLBR001 + SWI019) in patients with autoimmune conditions.

9 Apr 2025

Breakthrough nanoparticle delivery method targets brain inflammation for multiple conditions

Oregon State University researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions, including Alzheimer's disease, multiple sclerosis, Parkinson's disease and cancer cachexia.

9 Apr 2025