Bladder Cancer

In North America, bladder cancer is the fourth most common cancer in men and in the top ten for women. In the United States, approximately 70,000 patients are newly diagnosed with bladder cancer each year.

How is AI Used in the Treatment of Bladder Cancer?

Bladder cancer (BCa) is the most prevalent urinary tract malignancy and the most costly to cure. In recent years, AI algorithms have been used in BCa diagnosis and outcome prediction.

Muscle Invasive Bladder Cancer (MIBC)

Thromboembolism in Bladder Cancer

Endoscopic Imaging for Bladder Cancer

Bladder Cancer Biomarkers

Bladder Cancer Risk Factors

Muscle Invasive Bladder Cancer (MIBC) Diagnosis and Treatment

Bladder Cancer Types

What Causes Bladder Cancer?

Bladder Cancer Diagnosis

Bladder Cancer Treatment

What is Intravesical Therapy?

See more featured articles »

Bladder Cancer Genomics

Symptoms of Bladder Cancer

Bladder Cancer Histopathology

Non-Invasive Diagnostic Strategies for Bladder Cancer

What is Bladder Cancer?

Latest Bladder Cancer News and Research

New molecular insights reveal why some bladder cancers resist chemotherapy

About one quarter of patients with muscle-invasive bladder cancer (MIBC) may be treated and derive a benefit with the current standard chemotherapy.

31 Jul 2025

Gecko-inspired nanoparticles deliver targeted chemotherapy to tumors

As far back as the 4th Century B.C., Aristotle marveled at the nimble gecko's ability to "run up and down a tree in any way, even with the head downwards."

21 Jul 2025

Chemotherapy may trigger inflammatory response that fuels bladder cancer resistance

Chemotherapy used to target and kill bladder cancer cells may trigger an inflammatory response that ultimately may make the cancer more resistant to treatment, according to new research from scientists at Houston Methodist.

16 Jul 2025

Early-career physician-scientists receive major support from Damon Runyon Cancer Research Foundation

The Damon Runyon Cancer Research Foundation has named five new Damon Runyon Clinical Investigators.

14 Jul 2025

Advancing treatment for urothelial cancer with enfortumab vedotin and pembrolizumab

A new review was published in Volume 16 of Oncotarget on June 17, 2025, titled "Optimizing enfortumab vedotin plus pembrolizumab therapy."

2 Jul 2025

Urine-based DNA test predicts bladder cancer recurrence after immunotherapy

In a multi-institutional study published in Science Direct, researchers revealed that testing urine-based tumor DNA (utDNA) can help predict which bladder cancer patients are at higher risk for recurrence after treatment.

30 Jun 2025

Insilico Medicine begins clinical trial for AI-designed cancer drug ISM3412

Insilico Medicine, a clinical-stage biotechnology company driven by generative artificial intelligence (AI), today announces that the first patient has been dosed in a global multicenter clinical trial (NCT06414460) to evaluate ISM3412, a potentially best-in-class, AI-empowered MAT2A inhibitor with novel structure, in patients with locally advanced and metastatic solid tumors.

27 Jun 2025

Breakthrough therapy targets aggressive bladder cancer variant

Bladder tumors that have been excluded from clinical trials have a few things in common that could lead to new therapies.

17 Jun 2025

Global cancer experts gather in Kenya to improve care across Sub-Saharan Africa

The National Comprehensive Cancer Network (NCCN)-an alliance of leading cancer centers in the United States-is joining the African Cancer Coalition (ACC) to update cancer treatment recommendations during the American Cancer Society (ACS) 2025 Global Academy Regional Workshop: Sub-Saharan Africa, in Nairobi, Kenya, June 9-11.

10 Jun 2025

Y chromosome loss linked to poor cancer outcomes

When cancer cells in male patients and immune cells in their tumors both lose the Y chromosome, those patients tend to experience poorer outcomes than patients without Y chromosome loss, according to new findings from Cedars-Sinai investigators.

4 Jun 2025

New insights into decades-old bladder cancer treatment offers clues for immunotherapy

More than three decades ago, the U.S. Food and Drug Administration (FDA) approved Bacillus Calmette-Guérin (BCG) as the first immunotherapy against cancer. And it is still used today to treat early-stage bladder cancer.

29 May 2025

BCG immunotherapy reprograms bone marrow to boost cancer defense

29 May 2025

Cell Painting technology uncovers flavonoids with potential to treat bladder cancer

A team led by researchers at Baylor College of Medicine has identified flavonoids, natural compounds found in plants, that are toxic to bladder cancer cells cultured in the lab.

20 May 2025

Nectin4-targeted VHH-CAR-T cells show potency against bladder cancer

Announcing a new article publication for BIO Integration journal. Bladder cancer (BLCA) is one of the most common malignancies and the second most frequent urogenital tract tumor.

29 Apr 2025

Gut bacteria turn bile acids into allies against cancer

Bacteria naturally present in the human intestine, known as the gut microbiota, can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study led by Weill Cornell Medicine investigators.

16 Apr 2025

Study reveals CT scan overuse could account for 1 in 20 new US cancers

A new study projects that CT scans performed in the US in 2023 could cause around 103,000 future cancers, potentially accounting for 5% of all new cancer diagnoses. Researchers highlight that while individual risks are small, the population impact of unnecessary or high-dose CT imaging is significant.

15 Apr 2025

New study connects parasitic disease to genetic changes in the cervical lining

New research has revealed that Schistosoma haematobium (S. haematobium), a parasitic infection affecting millions globally, can trigger cancer-related gene activity in the cervical lining, with changes becoming even more pronounced after treatment.

12 Apr 2025

New blood test method improves accuracy of cancer detection

A new, error-corrected method for detecting cancer from blood samples is much more sensitive and accurate than prior methods and may be useful for monitoring disease status in patients following treatment, according to a study by Weill Cornell Medicine and New York Genome Center investigators.

11 Apr 2025

Laser-based infrared molecular fingerprinting detects common cancers

Cancer diagnoses traditionally require invasive or labor-intensive procedures such as tissue biopsies.

9 Apr 2025

Enfortumab vedotin and pembrolizumab show major benefits for urothelial carcinoma patients

Urothelium is the term for the mucous membrane that lines the urinary tract. This includes the renal pelvis, ureter, urinary bladder and the upper part of the urethra. In the vast majority of cases, urothelial carcinomas grow in the bladder (bladder carcinoma).

4 Apr 2025