Cytokines News and Research

Latest Cytokines News and Research

Mediterranean diet lowers COVID-19 risk, but its effect on symptoms and severity remains uncertain

Higher adherence to the Mediterranean diet is associated with a reduced risk of COVID-19, but its effects on symptom severity are less certain due to mixed results and study limitations.

27 Aug 2024

Unique strain of probiotic bacteria shows potential in combating inflammatory diseases

23 Aug 2024

Probiotic offers protection against intestinal damage

There is a critical unmet need to help tighten and maintain a healthy intestinal barrier and treat a leaky gut. Researchers have now found that a unique strain of probiotic bacteria, Bifidobacterium bifidum BB1, enhances intestinal barrier function and protects against penetration of bacteria and various harmful agents in the intestine. The findings, detailed in an article in The American Journal of Pathology, published by Elsevier, can help advance the development of novel, targeted, naturally occurring probiotic therapy for patients with inflammatory bowel disease (IBD) and other inflammatory diseases, such as fatty liver disease or alcoholic liver disease, that are associated with a leaky or disordered intestinal barrier.

23 Aug 2024

Research unveils how HMGA2 regulates stress responses in stem cells

Kumamoto University researchers have made a groundbreaking discovery that sheds light on how the HMGA2 gene - an essential transcriptional activator involved in chromatin modification - regulates stress responses in hematopoietic stem cells (HSCs), thereby enhancing blood cell production recovery.

22 Aug 2024

Understanding gluten's role in autoimmunity and inflammation

The interaction between humans and their environment, mediated by nutrition, plays a crucial role in regulating inflammatory responses.

21 Aug 2024

How persistent organic pollutants affect gut health: findings on metabolic disruptions and microbiota changes

Early life exposure to potent AHR agonists on gut microbiota and its potential effects on metabolic health later in life.

20 Aug 2024

Researchers reveal impact of genetic ancestry on breast cancer risk and cell diversity

Researchers map the diverse cell types present in healthy breast tissue to elucidate the role of genetic ancestry in breast cancer risk.

20 Aug 2024

Obesity-induced adipose inflammation boosts extracellular vesicle secretion

New research from the University of Eastern Finland sheds light on the mechanisms associating obesity with inflammation by exploring tiny membrane particles, known as extracellular vesicles, secreted by human adipocytes.

19 Aug 2024

Scientists discover key age-related biological shifts at 40 and 60

Researchers uncover the nonlinear dynamics of aging, revealing significant biological shifts at ages 40 and 60, offering new insights into age-related diseases.

16 Aug 2024

Engineering extracellular vesicles for potential treatment of type 1 diabetes

Within each of us lies an army of cells whose topmost duty is protecting against external pathogens and internal threats such as proliferating cancer cells.

14 Aug 2024

Impact of physical activity on gut microbiota in irritable bowel syndrome

The impact of different types and intensities of physical exercise on the gut microbiota and symptom alleviation in patients with irritable bowel syndrome.

14 Aug 2024

New targets for improved cancer immunotherapy

In the past two decades, immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, showing promising results against various solid tumors. This study reviews recent developments in ICIs, focusing on new targets like T cell immunoreceptors with Ig and ITIM domains (TIGIT), T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), and lymphocyte activation gene-3 (LAG-3). These targets aim to overcome resistance mechanisms limiting the effectiveness of current therapies, such as anti-PD-1 and anti-CTLA-4. By identifying and developing these new ICIs, researchers hope to improve treatment outcomes and provide new therapeutic options for cancer patients.

14 Aug 2024

Review explores potential for improved use of anti-angiogenic agents in cancer therapy

Most tumors release various signaling molecules to support their incessant growth, invasion, and metastasis.

9 Aug 2024

New insights into the role of cancer-associated fibroblasts in promoting lymphatic metastasis

Lymph node metastasis is a crucial factor in cancer progression, significantly affecting patient prognosis and treatment outcomes.

8 Aug 2024

The interplay of liver cancer stem cells and immune cells in tumor microenvironment

The complex dynamics between liver cancer stem cells (CSCs) and immune cells within the tumor microenvironment (TME) are central to the progression of liver cancer. These interactions are critical in creating an immunosuppressive setting that significantly impacts the response to immunotherapy. Liver CSCs, responsible for tumor initiation, metastasis, therapeutic resistance, and recurrence, exhibit heterogeneity and are characterized by various surface markers that contribute to their stemness and metastatic potential.

7 Aug 2024

Cytokines News and Research

Latest Cytokines News and Research

Mediterranean diet lowers COVID-19 risk, but its effect on symptoms and severity remains uncertain

Unique strain of probiotic bacteria shows potential in combating inflammatory diseases

Probiotic offers protection against intestinal damage

Research unveils how HMGA2 regulates stress responses in stem cells

Understanding gluten's role in autoimmunity and inflammation

How persistent organic pollutants affect gut health: findings on metabolic disruptions and microbiota changes

Researchers reveal impact of genetic ancestry on breast cancer risk and cell diversity

Obesity-induced adipose inflammation boosts extracellular vesicle secretion

Scientists discover key age-related biological shifts at 40 and 60

Engineering extracellular vesicles for potential treatment of type 1 diabetes

Impact of physical activity on gut microbiota in irritable bowel syndrome

New targets for improved cancer immunotherapy

Review explores potential for improved use of anti-angiogenic agents in cancer therapy

New insights into the role of cancer-associated fibroblasts in promoting lymphatic metastasis

The interplay of liver cancer stem cells and immune cells in tumor microenvironment

Harnessing oncolytic viruses for cancer immunotherapy to improve treatment outcomes

Cervical mucus biomarkers could improve early detection of cervical cancer

Review highlights the interplay of TGF-β and HIPPO pathways in liver regeneration and disease

Study reveals curcumin’s antidepressant effects in obese type 2 diabetes patients

Xanthones show promise in diabetes with antioxidant and anti-inflammatory properties

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

Cytokines News and Research

Latest Cytokines News and Research

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

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