Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Treatment of Depression

Depression and Sleep Length

Food Insecurity and Depression

How Does Your Diet Affect Depression?

Depression Diagnosis

Contributing Factors to Post-Adoption Depression

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

Prisoner Depression and Low Mood

Antidepressants and Weight Changes

Depression in children

How Can I Tell if My Child is Depressed?

See more featured articles »

Link Between Chronic Illness and Depression

Ghrelin and Depression

Treatment Options for Children with Depression

Genes and Depression

Can Depression and Anxiety Occur Together?

5 Facts You May Not Know About Depression

Supporting Children with Mental Health Disorders

Symptoms of Depression

Causes of Depression

Intrusive Thoughts and Depression

How is Depression in Children Diagnosed?

Situational Depression: Symptoms, Causes, Treatments

Latest Depression News and Research

Herbal remedies show promise for treating depression

This scoping review analyzes OTC products for depression, uncovering effective treatments and emphasizing the need for further studies on herbal efficacy.

4 Aug 2025

Dual tobacco use: Examining patterns in Hispanic and non-Hispanic Black men with chronic illness

Cannabis use is gaining popularity in the United States, driven by growing legalization, public acceptance and diverse methods of consumption.

4 Aug 2025

Mapping the brain’s serotonin switch could lead to better antidepressants

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights into how a critical brain receptor works at the molecular level and why that matters for mental health treatments.

1 Aug 2025

Subtle warning signs of MS can appear 15 years before diagnosis

The earliest warning signs of multiple sclerosis (MS) may emerge more than a decade before the first classical neurological symptoms occur, according to new research from the University of British Columbia.

1 Aug 2025

Genetic risk for depression linked to muted brain response to wins and losses

Novel imaging research indicates that young adults with a higher genetic risk for depression showed less brain activity in several areas when responding to rewards and punishments. The study also uncovered notable differences between men and women.

1 Aug 2025

Deadly opioid contaminants uncovered in Adelaide street drug supply

A synthetic opioid 1000 times more potent than morphine is infiltrating the street drug trade in Adelaide, Australia, sparking fears of a wave of overdoses that could be lethal.

1 Aug 2025

Chronically ill? In Kennedy’s view, it might be your own fault

On a recent weekday evening, Ashly Richards helped her 13-year-old son, Case, with homework. He did math problems and some reading, underscoring how much he's accomplished at his school for children with autism.

31 Jul 2025

Study confirms post-pandemic rise in disorders of gut-brain interaction

A new international study confirmed a significant post-pandemic rise in disorders of gut-brain interaction, including irritable bowel syndrome (IBS) and functional dyspepsia, according to the paper published in Clinical Gastroenterology and Hepatology.

30 Jul 2025

Eating more ultra-processed food links depression and diabetes

New research links ultra-processed food intake to increased diabetes risk in individuals with depression, highlighting the need for healthier dietary choices.

30 Jul 2025

Tribal groups assert sovereignty as feds crack down on gender-affirming care

At the Two Spirit Conference in northern Nevada in June, Native Americans gathered in support of the LGBTQ+ community amid federal and state rollbacks of transgender protections and gender-affirming health care.

30 Jul 2025

Exercise-based cardiac rehab benefits atrial fibrillation

Exercise-based cardiac rehabilitation lessens the severity, frequency, and recurrence of the most common form of irregular heart rhythm, atrial fibrillation, or AF for short, finds a pooled data analysis of the available research, published online in the British Journal of Sports Medicine.

30 Jul 2025

Changing the narrative on hormone-related mood disorders in women

In a wide-ranging Genomic Press Interview published today in Brain Medicine, Dr. David R. Rubinow recounts the serendipitous path that led him to overturn decades of medical assumptions about hormone-related mood disorders in women.

29 Jul 2025

Scientists uncover new brain mechanism driving PTSD and potential counter-drug

Did you know that patients with post traumatic stress disorder (PTSD) often struggle to forget traumatic memories, even long after the danger has passed? This failure to extinguish fear memories has long puzzled scientists and posed a major hurdle for treatment, especially since current medications targeting serotonin receptors offer limited relief for only a subset of patients.

29 Jul 2025

Moderate coffee and tea habits linked to sharper thinking in seniors

Moderate coffee intake and both moderate and high tea consumption are associated with a slower decline in fluid intelligence among older adults over nearly a decade. High coffee intake, however, is linked to a faster decline in cognitive function.

28 Jul 2025

Largest genetic study confirms biological basis of stuttering

The largest genetic analysis of stuttering has demonstrated a clear genetic basis for the speech disorder, highlighting neurological pathways of risk.

28 Jul 2025

Study reveals a strong link between early childhood adversities and depression in older Canadians

A new study of 3,500 Canadians aged 55 and older revealed a strong association between early childhood adversities and depression.

28 Jul 2025

California looked to them to close health disparities, then it backpedaled

Fortina Hernández is called "the one who knows it all." For more than two decades, the community health worker has supported hundreds of families throughout southeast Los Angeles by helping them sign up for food assistance, sharing information about affordable health coverage, and managing medications for their chronic illnesses.

28 Jul 2025

Persistent intense grief linked to higher healthcare use and mortality

Grief after the loss of a loved one is a natural response – an inevitable part of living and loving. But in a minority of the bereaved, grief is so overwhelming that it can lead to physical and mental illnes, even if they don't necessarily qualify for a diagnosis with the mental health condition 'prolonged grief disorder'.

28 Jul 2025

Which GLP-1 meds have the most side effects? Study of 60,000 Facebook posts gives answers

Researchers analyzed nearly 60,000 public Facebook posts to identify real-world adverse events linked to GLP-1 receptor agonist (GLP-1 RA) medications. Gastrointestinal symptoms were most common, while mental health concerns and tirzepatide-specific side effects were also flagged.

28 Jul 2025

Experts say you don’t need 10,000 steps, here’s the new magic number

A major systematic review finds that walking just 7,000 steps per day, rather than the traditional 10,000, can significantly reduce the risk of mortality, cardiovascular disease, dementia, and more. The analysis, published in The Lancet Public Health, provides an evidence-based and achievable target for adult health.

27 Jul 2025