Melanoma News and Research

Latest Melanoma News and Research

Gut microbes influence how well cancer patients respond to immunotherapy

Researchers discovered that gut microbiota-derived hexa-acylated LPS enhances the effectiveness of anti-PD-1 cancer immunotherapy, while penta-acylated LPS may suppress immune responses.

11 Feb 2025

Researchers discover strategy to slow brain metastases growth in melanoma

Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) in Elche, have identified a strategy to slow their progression, which could improve the response to current treatments.

7 Feb 2025

Neoantigen vaccine sparks powerful immune defense against kidney cancer

A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to long-lasting T cell expansion and no disease recurrence after 40 months.

6 Feb 2025

Inhibiting S6K2 gene offers potential treatment for drug-resistant melanoma

The lab of The Wistar Institute's Jessie Villanueva, Ph.D., has identified a new strategy for attacking treatment-resistant melanoma: inhibiting the gene S6K2. .

5 Feb 2025

Breakthrough personalized vaccine shows promising results in kidney cancer trial

Dana-Farber Cancer Institute researchers report that all nine patients in a clinical trial being treated for stage III or IV clear cell renal cell carcinoma (a form of kidney cancer), generated a successful anti-cancer immune response after initiation of a personalized cancer vaccine.

5 Feb 2025

Microbes in your gut could determine cancer treatment outcomes

Researchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment, with specific bacterial strains enhancing or inhibiting anti-tumor immunity.

4 Feb 2025

WSU scientists create genetically engineered mice to study cellular aging

Washington State University scientists have created genetically-engineered mice that could help accelerate anti-aging research.

4 Feb 2025

Green tea derived silver nanoparticles show promise against melanoma

Melanoma is a fast-progressing skin cancer characterized by a high mortality rate after metastasis. Local chemotherapy could be considered a therapeutic approach only in stage 0 of progression (in situ melanoma) and in the postoperative phase after surgical removal of suspected skin lesions.

3 Feb 2025

UIC scientists redesign asparaginase to minimize leukemia treatment side effects

University of Illinois Chicago scientists have redesigned a treatment for the most common pediatric leukemia to eliminate its severe side effects, like blood clots and liver damage.

31 Jan 2025

Researchers develop T cell growth method that enhances cancer-fighting ability in melanoma model

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

31 Jan 2025

Cancer-fighting virus T-VEC helps shrink tough-to-treat skin tumors

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell composition with low adverse events.

30 Jan 2025

Mayo Clinic researchers create organoid models for uveal melanoma study

Mayo Clinic researchers have developed organoid models to study uveal melanoma, one of the most common types of eye cancer in adults.

29 Jan 2025

T cells grown with new technique offer better cancer defense

Researchers from the University of Pittsburgh have developed a new way to grow T cells in the lab that enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared to those grown in traditional growth media.

28 Jan 2025

New therapy shows promise in treating basal cell carcinoma

Basal cell carcinomas, the most common form of skin cancer, occur in chronically sun-exposed areas such as the face.

27 Jan 2025

Breakthrough study targets tumor cell clusters to prevent metastasis

Certain tumor types do not remain at their point of origin but spread throughout the body and form metastases.

24 Jan 2025

Researchers identify ferroptosis as driver of osteocyte death in melanoma metastasis

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain.

23 Jan 2025

Researchers investigate a new combination therapy against cancer

A research team at the Medical University of Vienna led by Maria Sibilia has investigated a new combination therapy against cancer.

23 Jan 2025

Study offers insight into how senescent cells survive after cancer treatment

After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear.

22 Jan 2025

OncoAssure announces clinical validation of prostate cancer test

OncoAssure Ltd, an Irish medical diagnostic company, today announced the publication of new data, in the British Journal of Urology International Compass (BJUI Compass), which demonstrates the clinical validation of OncoAssure Prostate, a novel biopsy test which provides improved estimation of a patient’s risk of prostate cancer recurrence and allows for optimal treatment selection.

21 Jan 2025

Study finds anti-correlation of KLRG1 and PD-1 expression in tumor fighting T cells

A new research paper was published in Oncotarget's Volume 16 on January 20, 2025, titled "Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells."

21 Jan 2025