Pain News and Research

Latest Pain News and Research

Study uncovers how the brain amplifies pain from multiple sources

When pain strikes from multiple sources-such as a paper cut followed by contact with hot water-the experience can feel disproportionately intense. But is this agony merely additive, or does the brain integrate these signals in a way that amplifies suffering?

25 Jun 2025

Study finds nearly double risk of depression and anxiety in autoimmune patients

Living with an autoimmune disease is linked to a near doubling in the risk of persistent mental health issues, such as depression, generalised anxiety, and bipolar disorder, with these risks higher in women than in men, finds a large population-based UK study, published in the open access journal BMJ Mental Health.

25 Jun 2025

How a novel reaction in E. coli helps recycle plastic into paracetamol

Researchers have demonstrated that E. coli can perform a biocompatible Lossen rearrangement, enabling phosphate-catalysed conversion of synthetic substrates into valuable compounds. This approach allows engineered bacteria to upcycle PET plastic waste into paracetamol, highlighting a novel intersection of chemistry and biotechnology.

24 Jun 2025

Flexible wireless implant offers hope for chronic pain sufferers

Chronic pain is a debilitating condition that severely impacts quality of life, often leading to reliance on opioid medications with their severe side effects and addiction risks.

24 Jun 2025

Genetically engineered skin grafts help heal chronic wounds in patients with epidermolysis bullosa

Skin grafts genetically engineered from a patient's own cells can heal persistent wounds in people with an extremely painful dermatologic disease, a Stanford Medicine-led clinical trial has shown.

23 Jun 2025

Low FODMAP diet shown to improve gastrointestinal symptoms in women with endometriosis

A low FODMAP diet developed by Monash University researchers for irritable bowel syndrome (IBS) has been shown to improve gastrointestinal symptoms in women with endometriosis.

23 Jun 2025

Endometriosis linked to higher odds of autoimmune conditions

New research links endometriosis to autoimmune diseases, revealing shared mechanisms that may lead to earlier diagnosis and targeted treatments for patients.

23 Jun 2025

Many older people embrace vaccines. Research is proving them right.

Kim Beckham, an insurance agent in Victoria, Texas, had seen friends suffer so badly from shingles that she wanted to receive the first approved shingles vaccine as soon as it became available, even if she had to pay for it out-of-pocket.

23 Jun 2025

Federal proposals threaten provider taxes, key source of Medicaid funding for states

Republican efforts to restrict taxes on hospitals, health plans, and other providers that states use to help fund their Medicaid programs could strip them of tens of billions of dollars.

23 Jun 2025

Diabetes medication shows promise in cutting migraine days by more than half

A diabetes medication that lowers brain fluid pressure has cut monthly migraine days by more than half, according to a new study presented today at the European Academy of Neurology (EAN) Congress 2025.

20 Jun 2025

New toolkit aims to transform opioid education through patient collaboration

It's difficult to overstate the corrosive impact of Canada's ongoing opioid crisis. Since 2016, there have been over 40,000 opioid-related deaths across the country, devastating Canadian families from all walks of life. Opioid-related hospitalizations and calls to paramedics have ballooned.

20 Jun 2025

New brain study explains why some pain becomes chronic

A new study reveals that when we experience short-term (acute) pain, the brain has a built-in way to dial down pain signals - like pressing the brakes - to keep them from going into overdrive.

20 Jun 2025

Driving breakthroughs for the NF community at the 2025 NF Conference

A new era is unfolding for the NF community. With two FDA-approved treatments now on the market - including the first-ever therapy for adults with NF1 - and cutting-edge advances in AI, drug repositioning, and precision medicine, momentum is building like never before.

20 Jun 2025

Sleep deprivation alters brain response to pain in migraine sufferers

For the first time, researchers have studied what happens in the brains of people who have migraines when they haven't slept enough.

19 Jun 2025

Self-regulating mRNA medicineadjusts protein production based on disease-related signals

Researchers develop a self-regulating mRNA medicine that adjusts protein production based on disease-related signals.

19 Jun 2025

New guidance aims to improve blood clot prevention in chronic limb-threatening ischemia patients

A new statement from leading heart and blood vessel experts in Europe is providing clinical guidance for treatments to prevent blood clots in patients with a serious condition called chronic limb-threatening ischaemia (CLTI), after they have had procedures to restore blood flow in their lower limbs.

19 Jun 2025

Newborns feel pain before fully understanding it

Brain networks responsible for sensing, understanding, and responding emotionally to pain develop at different rates in infants, with the conscious understanding of pain not fully developed until after birth, finds a new study led by UCL (University College London) researchers.

19 Jun 2025

New meta-analysis highlights effective non-drug therapies for knee osteoarthritis

Knee braces, water therapy and exercise are the most promising non-drug therapies for treating knee osteoarthritis, according to a new meta-analysis publishing June 18, 2025 in the open-access journal PLOS One by Yuan Luo of the First People's Hospital of Neijiang, China.

19 Jun 2025

Global guideline released by WHO on managing sickle cell disease in pregnancy

The World Health Organization (WHO) today released its first-ever global guideline on the management of sickle cell disease (SCD) during pregnancy, addressing a critical and growing health challenge that can have life-threatening consequences for both women and babies.

19 Jun 2025

New dual-adjuvant vaccine strategy offers hope in the fight against HIV

In the quest to develop an effective HIV vaccine, scientists from Scripps Research have made a significant leap forward. They found that a two-part delivery strategy can train the immune system to produce a stronger response to HIV, offering new hope in the fight against one of the world's most elusive viruses.

19 Jun 2025