Scleroderma News and Research

Latest Scleroderma News and Research

Actelion launches new 20 mcg/mL Ventavis formulation

Actelion Pharmaceuticals US, Inc., today announced the first commercial sales of a new 20 microgram per milliliter (mcg/mL) formulation of Ventavis(R), for the treatment of New York Heart Association Class III and IV pulmonary arterial hypertension (PAH). This increased strength formulation delivers the same dose of Ventavis in half the volume, which is expected to reduce inhalation time and further support patient compliance.

2 Sep 2009

Drug derived from the hydrangea root shows promise for autoimmune disorders

A drug derived from the hydrangea root, used for centuries in traditional Chinese medicine, shows promise in treating autoimmune disorders, report researchers from the Program in Cellular and Molecular Medicine and the Immune Disease Institute at Children's Hospital Boston (PCMM/IDI), along with the Harvard School of Dental Medicine.

4 Jun 2009

Cultured stem cells and bioengineered skin used to successfully treat scleroderma

Scleroderma is an autoimmune disease that leads to thickening and severe scarring of skin as well as thickening and failure of internal organs, including the lungs, heart, kidneys and intestines.

5 Mar 2009

New study using combination of bioengineered skin and stem cells shows promise in treatment of non-healing wounds

Scleroderma is an autoimmune disease that leads to thickening and severe scarring of skin as well as thickening and failure of internal organs, including the lungs, heart, kidneys and intestines.

5 Mar 2009

Tumor suppressor may weaken fibrotic disease

New research reveals a critical cellular signaling pathway that is responsible for generating excess connective tissue in multiple organs, similar to what is seen in human patients with scleroderma.

18 Feb 2009

UV light therapy is as beneficial for darker skin as lighter skin

An analysis of more than 100 patients has confirmed for the first time that darker-skinned patients benefit as those with lighter skin when given light therapy for morphea and related diseases, UT Southwestern Medical Center researchers show.

8 Jul 2008

Mothers and offspring can share cells throughout life - with positive and negative effects

Cutting the umbilical cord doesn't necessarily sever the physical link between mother and child. Many cells pass back and forth between the mother and fetus during pregnancy and can be detected in the tissues and organs of both even decades later. This mixing of cells from two genetically distinct individuals is called microchimerism. The phenomenon is the focus of an increasing number of scientists who wonder what role these cells play in the body.

30 Apr 2008

New understanding of systemic sclerosis

Systemic sclerosis (SSc), also known as scleroderma, is characterized by the formation of fibrosis, or scar tissue, on internal organs as well as the skin.

15 Apr 2008

Men get autoimmune diseases, too!

What do former President George H.W. Bush, Fox Business News anchor Neil Cavuto, comedian and actor Bernie Mac, Poison lead singer and reality television star Bret Michaels and Seattle Seahawks wide receiver Bobby Engram have in common?

4 Apr 2008

Methamphetamine use and pulmonary arterial hypertension

The Pulmonary Hypertension Association (PHA), in conjunction with leading pulmonary hypertension specialists, has announced the launch of an educational campaign to raise awareness of the association between pulmonary arterial hypertension (PAH) and stimulant use, particularly methamphetamine use.

24 Mar 2008

Fibrosis in the liver stopped and reversed by researchers

University of California, San Diego researchers have proven in animal studies that fibrosis in the liver can be not only stopped, but reversed.

28 Dec 2007

New method for early diagnosis of pulmonary hypertension

Researchers at the University of Granada ( UGR ) from the Systemic Autoimmune Diseases Unit and the Cardiology Service of the Hospital Clínico San Cecilio in Granada have developed an innovative system which will help doctors make the earliest diagnosis of pulmonary hypertension possible, which is the main cause of death for patients suffering from scleroderma, a rare disease which affects approximately 1,200 out of every million people.

14 Nov 2007

Discovery on manipulating skin tone and color

In the timeless quest for healthier, younger looking skin, scientists from the University of Cincinnati and Tokyo Medical University have made an important discovery toward manipulating skin tone and color.

24 Aug 2007

Raynaud's disease review by Mayo Clinic Health Letter

There's a medical reason behind cold fingers and toes, when a chill seems to instantly turn extremities white.

10 May 2007

Green tea may help protect against Sjogren's syndrome

They found significantly less salivary gland damage in a group treated with green tea extract, suggesting a reduction of the Sjogren's symptom commonly referred to as dry mouth. Dry mouth can also be caused by certain drugs, radiation and other diseases.

20 Apr 2007

Rep. Dave Weldon comments on stem therapy and type I diabetes

In yet another advance in adult stem cell therapy, the Journal of the American Medical Association (JAMA) today released a study in which 14 of 15 Juvenile Diabetes patients demonstrated significant improvement as a result of an adult stem cell treatment.

11 Apr 2007

Atorvastatin may increase new blood vessel formation

Systemic sclerosis (SSc), also known as scleroderma, is an uncommon and confounding disease characterized by excessive fibrous tissue formation and vascular abnormalities.

6 Jun 2006

Antifibrotic effect of hepatocyte growth factor is impaired in lung fibroblasts isolated from African-Americans

Of the more than 40,000 persons who die each year in the U.S. from pulmonary fibrosis, the mortality rate among African-Americans is twice as high Caucasians.

11 Apr 2006

Paclitaxel may help treat scleroderma

Using a novel model for scleroderma, researchers from Duke University Medical Center have discovered two important insights into this devastating disorder - the anti-cancer drug paclitaxel (Taxol) may prevent the skin thickening and small blood vessel destruction that characterizes the disease.

1 Nov 2005

Cyclophosphamide may be a possible therapy for scleroderma

A drug that suppresses the immune system and reduces inflammation has been shown to be effective in treating lung disease associated with the devastating connective tissue disease scleroderma, according to results presented at the American Thoracic Society International Conference on May 23.

24 May 2005