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Johns Hopkins uncovers protein's unexpected role in brain signaling

Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting brain cells to communicate at the right time and place in experiments with genetically engineered mice.

4 Aug 2025

New research highlights exercise's broad impact in Parkinson's disease

It was the early 2000s when researchers first showed that exercise can help relieve the tremors that are common with Parkinson's Disease.

4 Aug 2025

Dual tobacco use: Examining patterns in Hispanic and non-Hispanic Black men with chronic illness

Cannabis use is gaining popularity in the United States, driven by growing legalization, public acceptance and diverse methods of consumption.

4 Aug 2025

New Swiss study probes lingering fatigue after Legionnaires' disease

Researchers in Switzerland launched the LongLEGIO study to compare the long-term health impacts of Legionnaires’ disease and other bacterial pneumonias. Baseline data reveal key differences in comorbidities and quality of life between the groups, with follow-up underway.

4 Aug 2025

Can your diet and health change your breast milk? Review uncovers the key maternal and birth factors

This review highlights how maternal, obstetrical, and neonatal factors influence the energy and macronutrient content of breast milk. The findings underscore significant variability in milk composition, with implications for tailored nutritional support in early life.

3 Aug 2025

Metformin’s blood sugar control starts in the brain, not just the liver, study finds

Low, clinically relevant doses of metformin lower blood glucose by inhibiting the Rap1 protein in specific neurons of the hypothalamus, revealing a brain-first mechanism. This action is essential for metformin’s effect at therapeutic doses and highlights new directions for diabetes treatment.

3 Aug 2025

AI spots hidden diabetes risk even when test results look normal

Researchers used continuous glucose monitoring and multimodal data from over 3,000 people to reveal hidden patterns in glucose spikes across normoglycemia, prediabetes, and type 2 diabetes. Their AI-driven model exposed high individual variability and offers a personalized path for early detection and prevention of diabetes.

3 Aug 2025

Immune molecule found to play a key role in regulating inflammation in rheumatoid arthritis

Researchers at Kyoto University have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis (RA).

1 Aug 2025

Mapping the brain’s serotonin switch could lead to better antidepressants

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights into how a critical brain receptor works at the molecular level and why that matters for mental health treatments.

1 Aug 2025

Key protein found to guide melanoma cells during spread

Researchers have discovered a protein which is critical for steering melanoma cancer cells as they spread throughout the body.

1 Aug 2025

Study uncovers inflammatory pathways that contribute to asthma flare-ups in children

A recent multicenter clinical trial has uncovered inflammatory pathways that contribute to asthma flare-ups in children that occur despite treatment, according to findings published in JAMA Pediatrics.

1 Aug 2025

Unraveling the mysteries of post-acute infection syndromes

In recent years, doctors and scientists are increasingly studying long-lasting illnesses that begin after someone recovers from an infection.

1 Aug 2025

New approach preserves insulin-producing cells in diabetes model

Scientific breakthroughs in one disease don't always shed light on treating other diseases. But that's been the surprising journey of one Mayo Clinic research team.

1 Aug 2025

New study shows brain's role in diabetic ketoacidosis

More than a decade ago, researchers found that an acute complication of type 1 diabetes, diabetic ketoacidosis (DKA), can be resolved with the hormone leptin, even in the absence of insulin.

1 Aug 2025

Narrow Medicare drug coverage linked to worse outcomes in MS patients

Medicare drug plans are increasingly excluding coverage of new specialty drugs that treat complex conditions like cancers and autoimmune diseases. New research from the USC Schaeffer Center shows how these barriers may come at a cost to patients' health.

1 Aug 2025

Subtle warning signs of MS can appear 15 years before diagnosis

The earliest warning signs of multiple sclerosis (MS) may emerge more than a decade before the first classical neurological symptoms occur, according to new research from the University of British Columbia.

1 Aug 2025

Genetic risk for depression linked to muted brain response to wins and losses

Novel imaging research indicates that young adults with a higher genetic risk for depression showed less brain activity in several areas when responding to rewards and punishments. The study also uncovered notable differences between men and women.

1 Aug 2025

Study explores the impact of COVID-19 pandemic among youth and parents across the U.S. Midwest

The COVID-19 pandemic upended life for individuals and communities worldwide. Social isolation, health mandates, illness, and economic hardships took a toll on the well-being of families and children, but there were also silver linings to people's experiences.

1 Aug 2025

New study confirms cardiovascular safety of COVID-19 vaccines

The incidence of heart attacks and strokes was lower after COVID-19 vaccination than before or without vaccination, according to a new study involving nearly the whole adult population of England.

1 Aug 2025

Unlocking the power of stereochemistry to improve mRNA drug delivery

A team from the Max-Planck-Institut für Kohlenforschung, Hokkaido University, and Osaka University has discovered that subtle differences in molecular structure can have a major impact on the performance of mRNA-based drugs.

1 Aug 2025