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Unlocking the power of stereochemistry to improve mRNA drug delivery

A team from the Max-Planck-Institut für Kohlenforschung, Hokkaido University, and Osaka University has discovered that subtle differences in molecular structure can have a major impact on the performance of mRNA-based drugs.

1 Aug 2025

Deadly opioid contaminants uncovered in Adelaide street drug supply

A synthetic opioid 1000 times more potent than morphine is infiltrating the street drug trade in Adelaide, Australia, sparking fears of a wave of overdoses that could be lethal.

1 Aug 2025

Nordic study finds nasogastric tubes reduce complications after esophageal cancer surgery

In the largest Nordic study to date concerning esophageal cancer surgery, the researchers found clear evidence that decompression with a nasogastric tube is associated with less serious complications.

1 Aug 2025

Characterization of antibodies targeting ASO modifications for intracellular trafficking

A new article in the peer-reviewed journal Nucleic Acid Therapeutics describes the characterization of antibodies targeting antisense oligonucleotide (ASO) phosphorothioate and 2'-methoxyehtyl modifications for intracellular trafficking and biodistribution studies.

1 Aug 2025

Synthetic torpor moves closer to real-world medical use

Nature is often the best model for science. For nearly a century, scientists have been trying to recreate the ability of some mammals and birds to survive extreme environmental conditions for brief or extended periods by going into torpor, when their body temperature and metabolic rate drop, allowing them to preserve energy and heat.

1 Aug 2025

High potency cannabis tied to greater use and risk in US youth

A new study published today in the scientific journal Addiction has found that young adults in the US do not 'titrate' when using strong cannabis.

1 Aug 2025

Young human serum requires bone marrow for skin rejuvenation effects

A new research paper featured on the cover of Volume 17, Issue 7 of Aging (Aging-US) was published on July 25, 2025, titled "Systemic factors in young human serum influence in vitro responses of human skin and bone marrow-derived blood cells in a microphysiological co-culture system."

1 Aug 2025

AI-designed protein activates Notch signaling pathway to boost T-cell production

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in T-cell development and function.

1 Aug 2025

The vicious circle of aging and metabolic dysfunction-associated steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) and aging are locked in a vicious circle: senescence of liver cells accelerates fat accumulation, inflammation and fibrosis, while chronic steatosis in turn hastens hepatic decline.

1 Aug 2025

Study finds rapid spread of antibiotic-resistant bacteria among malnourished children in Niger

A new study led by researchers at the Ineos Oxford Institute for antimicrobial research (IOI) has found that antimicrobial resistant bacteria is spreading rapidly among children being treated for severe malnutrition in a hospital facility in Niger.

1 Aug 2025

Hearing loss impacts employment and income among young adults

Hearing loss is the most common form of sensory disability. Approximately 1.6 billion people around the world currently live with from some degree of hearing loss, and the WHO has forecast that this number will rise to 2.5 billion by 2050.

1 Aug 2025

Salk Institute's ShortStop revolutionizes genetic search

Proteins sustain life as we know it, serving many important structural and functional roles throughout the body. But these large molecules have cast a long shadow over a smaller subclass of proteins called microproteins.

1 Aug 2025

Spinning's positive impact on hip osteoarthritis uncovered

A new study by Bournemouth University (BU) and University Hospitals Dorset (UHD) has revealed the benefits of spinning for patients with hip osteoarthritis. The study was funded by the National Institute for Health Research (NIHR) and will be published in Lancet Rheumatology at 23:30 UK time on Thursday 31st July 2025.

1 Aug 2025

Beneficial gut bacteria found to suppress harmful microbes

Intestinal bacteria are important for human health as they help digest food and regulate immune function. Thus, in recent years, it has become clear that gut microbiota dysbiosis, an imbalance in types and composition of intestinal bacteria, is associated with digestive disorders and other diseases.

1 Aug 2025

Researchers uncover PSAT1 gene as key to heart repair post-heart attack

Heart attacks remain a leading cause of death and disability worldwide. The permanent loss of heart muscle cells-known as cardiomyocytes-and the heart's limited regenerative capacity often led to chronic heart failure.

1 Aug 2025

Efficacy of methylprednisolone doses in severe Mycoplasma Pneumonia

Investigators compare efficacy of low- versus high-dose of methylprednisolone in preventing pulmonary lesions in children with severe Mycoplasma pneumoniae pneumonia

1 Aug 2025

RMIT's wearable tech fights infection with smart sensors

Researchers from RMIT University have developed a wearable wound monitoring device with integrated sensors that could reduce infection risks by minimising the need for frequent physical contact.

1 Aug 2025

Scientists finally define what it means to be flexitarian

Researchers conducted a systematic review to develop a clear, evidence-based definition of the “flexitarian” diet, identifying it as consuming animal products at least once a month but less than once a week. Analysis of 42 countries’ dietary guidelines revealed that while “flexitarian” is not officially recognized, many nations implicitly support plant-forward eating by recommending reduced red meat consumption.

31 Jul 2025

Exercise-based cardiac rehab cuts atrial fibrillation recurrence and boosts quality of life, study finds

Exercise-based cardiac rehabilitation reduces recurrence, severity, and burden of atrial fibrillation, while improving mental quality of life and exercise capacity. However, it does not impact mortality or serious adverse events and evidence for physical quality of life remains uncertain.

31 Jul 2025

Researchers find indoor air teeming with invisible microplastics

A groundbreaking study reveals that invisible microplastics in homes and cars may be entering our lungs by the tens of thousands each day, underscoring a hidden risk of modern indoor life.

31 Jul 2025