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Genetic risk for depression linked to muted brain response to wins and losses

Novel imaging research indicates that young adults with a higher genetic risk for depression showed less brain activity in several areas when responding to rewards and punishments. The study also uncovered notable differences between men and women.

1 Aug 2025

Study explores the impact of COVID-19 pandemic among youth and parents across the U.S. Midwest

The COVID-19 pandemic upended life for individuals and communities worldwide. Social isolation, health mandates, illness, and economic hardships took a toll on the well-being of families and children, but there were also silver linings to people's experiences.

1 Aug 2025

New study confirms cardiovascular safety of COVID-19 vaccines

The incidence of heart attacks and strokes was lower after COVID-19 vaccination than before or without vaccination, according to a new study involving nearly the whole adult population of England.

1 Aug 2025

Unlocking the power of stereochemistry to improve mRNA drug delivery

A team from the Max-Planck-Institut für Kohlenforschung, Hokkaido University, and Osaka University has discovered that subtle differences in molecular structure can have a major impact on the performance of mRNA-based drugs.

1 Aug 2025

Deadly opioid contaminants uncovered in Adelaide street drug supply

A synthetic opioid 1000 times more potent than morphine is infiltrating the street drug trade in Adelaide, Australia, sparking fears of a wave of overdoses that could be lethal.

1 Aug 2025

Nordic study finds nasogastric tubes reduce complications after esophageal cancer surgery

In the largest Nordic study to date concerning esophageal cancer surgery, the researchers found clear evidence that decompression with a nasogastric tube is associated with less serious complications.

1 Aug 2025

Characterization of antibodies targeting ASO modifications for intracellular trafficking

A new article in the peer-reviewed journal Nucleic Acid Therapeutics describes the characterization of antibodies targeting antisense oligonucleotide (ASO) phosphorothioate and 2'-methoxyehtyl modifications for intracellular trafficking and biodistribution studies.

1 Aug 2025

Synthetic torpor moves closer to real-world medical use

Nature is often the best model for science. For nearly a century, scientists have been trying to recreate the ability of some mammals and birds to survive extreme environmental conditions for brief or extended periods by going into torpor, when their body temperature and metabolic rate drop, allowing them to preserve energy and heat.

1 Aug 2025

High potency cannabis tied to greater use and risk in US youth

A new study published today in the scientific journal Addiction has found that young adults in the US do not 'titrate' when using strong cannabis.

1 Aug 2025

Young human serum requires bone marrow for skin rejuvenation effects

A new research paper featured on the cover of Volume 17, Issue 7 of Aging (Aging-US) was published on July 25, 2025, titled "Systemic factors in young human serum influence in vitro responses of human skin and bone marrow-derived blood cells in a microphysiological co-culture system."

1 Aug 2025

AI-designed protein activates Notch signaling pathway to boost T-cell production

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in T-cell development and function.

1 Aug 2025

The vicious circle of aging and metabolic dysfunction-associated steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) and aging are locked in a vicious circle: senescence of liver cells accelerates fat accumulation, inflammation and fibrosis, while chronic steatosis in turn hastens hepatic decline.

1 Aug 2025

Study finds rapid spread of antibiotic-resistant bacteria among malnourished children in Niger

A new study led by researchers at the Ineos Oxford Institute for antimicrobial research (IOI) has found that antimicrobial resistant bacteria is spreading rapidly among children being treated for severe malnutrition in a hospital facility in Niger.

1 Aug 2025

Hearing loss impacts employment and income among young adults

Hearing loss is the most common form of sensory disability. Approximately 1.6 billion people around the world currently live with from some degree of hearing loss, and the WHO has forecast that this number will rise to 2.5 billion by 2050.

1 Aug 2025

Salk Institute's ShortStop revolutionizes genetic search

Proteins sustain life as we know it, serving many important structural and functional roles throughout the body. But these large molecules have cast a long shadow over a smaller subclass of proteins called microproteins.

1 Aug 2025

Spinning's positive impact on hip osteoarthritis uncovered

A new study by Bournemouth University (BU) and University Hospitals Dorset (UHD) has revealed the benefits of spinning for patients with hip osteoarthritis. The study was funded by the National Institute for Health Research (NIHR) and will be published in Lancet Rheumatology at 23:30 UK time on Thursday 31st July 2025.

1 Aug 2025

Beneficial gut bacteria found to suppress harmful microbes

Intestinal bacteria are important for human health as they help digest food and regulate immune function. Thus, in recent years, it has become clear that gut microbiota dysbiosis, an imbalance in types and composition of intestinal bacteria, is associated with digestive disorders and other diseases.

1 Aug 2025